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HFEA 表示體外受精后雙胞胎出生率處于歷史最低水平

游海 2022-2-16 17:22 試管之家 查看: 82 評論: 0

摘要:   根據人類受精和胚胎學管理局(HFEA)的數據,體外受精后多胞胎的比例已大幅下降至6%?! ∮亩喟盗恳堰_到歷史最低水平。'這是英國醫療保健的重大成功。HFEA主席Julia Chain解釋說,多胞胎對患者和未出生的 ...
  根據人類受精和胚胎學管理局(HFEA)的數據,體外受精后多胞胎的比例已大幅下降至6%。

  英國的多胞胎數量已達到歷史最低水平。'這是英國醫療保健的重大成功。HFEA主席Julia Chain解釋說,多胞胎對患者和未出生的嬰兒都可能是危險的,并且會給NHS帶來額外的負擔。

  上周發布的HFEA新報告總結了2015年至2019年間體外受精后多胞胎的數據。多胞胎早產的風險更高,這可能導致長期的健康問題,例如腦癱和學習困難。孩子。多胎妊娠的女性患先兆子癇和晚期流產的風險也更高。HFEA報告稱,從1990年代到2019年,英國的多胎出生率大幅下降,從28%下降到僅6%。

  重要的是,HFEA發現,一次只移植一個胚胎來減少多胞胎似乎對成功率沒有影響。相反,試管嬰兒的成功率穩步提高。此外,使用NHS的患者和私人資助治療的患者的體外受精成功率沒有差異。然而,與NHS患者(5%)相比,年輕的私人資助患者(9%)的多胞胎率更高。

  從歷史上看,IVF后的多胎出生率一直高于自然受孕后的多胎出生率,因為多個胚胎同時轉移到子宮中。除特殊情況外,三重胚胎移植的做法在2003年僅限于40歲以下的患者。然后在2007年,HFEA的“一次一個”運動鼓勵診所進行單胚胎移植并冷凍其他可行的胚胎。此后,單胚胎移植將所有年齡組的多胞胎率限制在1%到3%之間。

  然而,HFEA的報告確實顯示,所有人口統計數據中的多胎出生率并沒有均勻下降。黑人患者的多胞胎和多胚胎移植率顯著高于其他種族群體,比率為12%,而其他群體的平均比率為10%。因此,黑人婦女及其嬰兒仍然面臨著更高的多胞胎并發癥風險。

  Chain確認HFEA將“鼓勵診所審查他們的多胞胎策略,特別是與少數民族患者有關的策略,因為我們希望為所有患者提供公平的競爭環境?!?/div>

  原文:

HFEA says twin births are at an all-time low

  The proportion of multiple births following IVF has fallen dramatically to six percent,according to the Human Fertilisation and Embryology Authority(HFEA).

  The number of multiple births has reached an all-time low in the UK.'This is a major success for UK healthcare.Multiple births can be dangerous for both patients and unborn babies and can put an additional burden on the NHS,'explained Julia Chain,chair of the HFEA.

  The new report from the HFEA,published last week,summarised data on multiple births following IVF between 2015 and 2019.Multiple births carry a higher risk of prematurity,which can result in long-term health issues such as cerebral palsy and learning difficulties in the child.Women carrying multiple pregnancies are also at a higher risk of pre-eclampsia and late miscarriage.The HFEA reported a substantial reduction in the UK multiple birth rate from the 1990s to 2019,falling from 28 percent to just six percent.

  Importantly,the HFEA found that the reduction in multiple births by transferring only one embryo at a time does not seem to have had an impact on success rates.On the contrary,IVF success rates have steadily improved.In addition,no difference was found between IVF success rates for patients using the NHS and patients whose treatment was funded privately.However,the rate of multiple births was higher among young,privately funded patients(nine percent)compared to NHS patients(five percent).

  Historically,multiple birth rates following IVF have been higher than multiple birth rates following natural conception,because of multiple embryos being transferred into the womb at once.The practice of triple embryo transfer was restricted in 2003 to patients under 40,apart from in exceptional circumstances.Then in 2007,the HFEA's'One at a Time'campaign encouraged clinics to practise single embryo transfer and freeze other viable embryos.Single embryo transfers have since limited the rate of multiple births to between one and three percent across all age groups.

  The HFEA's report did,however,reveal that multiple birth rates have not fallen evenly across all demographics.Multiple births and multiple embryo transfers were significantly higher in black patients than in other ethnic groups,at a rate of 12 percent compared with an average of ten percent across other groups.Consequently,black women and their babies remain at a higher risk from the complications of a multiple birth.

  Chain affirmed that the HFEA will'encourage clinics to review their multiple birth strategies,particularly in relation to patients from ethnic minority groups as we want to achieve a level playing field for all patients.'

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